EGPI-1, a novel eIF4E/eIF4G interaction inhibitor, inhibits lung cancer cell growth and angiogenesis through Ras/MNK/ERK/eIF4E signaling pathway

Qi, XJ; Zhang, SN; Chen, ZK; Wang, LJ; Zhu, WY; Yin, CJ; Fan, JT; Wu, XC; Wang, J; Guo, CL

Guo, CL (通讯作者)，Qingdao Univ Sci & Technol, Coll Chem Engn, Dept Pharm, Qingdao 266042, Peoples R China.;Wang, J (通讯作者)，Baotou Teachers Coll, Dept Biol Sci & Technol, Baotou 014030, Peoples R China.

CHEMICO-BIOLOGICAL INTERACTIONS, 2022; 352 ():

Abstract

eIF4E plays an important role in regulating tumor growth and angiogenesis, and eIF4E is highly expressed in a variety of lung cancer cell lines. siRNA......

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