[C-11](R)-Rolipram positron emission tomography detects DISC1 inhibition of phosphodiesterase type 4 in live Disc1 locus-impaired mice

Ooms, M; Tsujikawa, T; Lohith, TG; Mabins, SN; Zoghbi, SS; Sumitomo, A; Jaaro-Peled, H; Kimura, Y; Telu, S; Pike, VW; Tomoda, T; Innis, RB; Sawa, A; Fujita, M

Fujita, M (reprint author), NIMH, Mol Imaging Branch, 10 Ctr Dr,Bldg 10,Rm B1D43, Bethesda, MD 20892 USA.

JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM, 2019; 39 (7): 1306

Abstract

Although still a matter of controversy, disrupted in schizophrenia protein 1 (DISC1) was suggested as a potential inhibitor of phosphodiesterase 4 (PD......

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