Synthesis and biological evaluation of novel aromatic amide derivatives as potential BCR-ABL inhibitors

Wang, XJ; Xu, Z; Feng, J; Pan, G; He, XB; Lv, MX; Chen, HJ; Jiang, WT; Ji, J; Yang, ML

Ji, J (通讯作者)，Jiangsu Ocean Univ, Coll Pharm, Lianyungang 222000, Peoples R China.;Yang, ML (通讯作者)，Nanjing Med Univ, Kangda Coll, Dept Pharm, Lianyungang 222000, Peoples R China.

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2023; 81 ():

Abstract

BCR-ABL1 kinase is a key driver of the pathophysiology of chronic myeloid leukemia (CML). Current treatments need to broaden the chemical diversity of......

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