PSMG2-controlled proteasome-autophagy balance mediates the tolerance for MEK-targeted therapy in triple-negative breast cancer

Wang, XY; Yu, J; Liu, XW; Luo, D; Li, YC; Song, LL; Jiang, X; Yin, XM; Wang, Y; Chai, L; Luo, T; Jing, J; Shi, HB

Jing, J; Shi, HB (通讯作者),Sichuan Univ, West China Hosp, Clin Res Ctr Breast, Lab Integrat Med,State Key Lab Biotherapy, Chengdu 610041, Sichuan, Peoples R China.;Jing, J; Shi, HB (通讯作者),Collaborat Innovat Ctr, Chengdu 610041, Sichuan, Peoples R China.

CELL REPORTS MEDICINE, 2022; 3 (9):

Abstract

Although the MAPK pathway is aberrantly activated in triple-negative breast cancers (TNBCs), the clinical outcome of MEK-targeted therapy is still poo......

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