Spleen tyrosine kinase (SYK) inhibitor PRT062607 protects against ovariectomy-induced bone loss and breast cancer-induced bone destruction

Xie, G; Liu, WJ; Lian, Z; Xie, DT; Yuan, GX; Ye, JJ; Lin, ZH; Wang, WD; Zeng, JC; Shen, HX; Wang, XJ; Feng, HT; Cong, W; Yao, GF

Yao, GF (corresponding author), Shantou Univ, Coll Med, Affiliated Hosp 2, Dept Orthoped, Shantou, Guangdong, Peoples R China.; Cong, W (corresponding author), Shanghai Univ, Inst Translat Med, Shanghai, Peoples R China.

BIOCHEMICAL PHARMACOLOGY, 2021; 188 ():

Abstract

Osteolytic diseases, including breast cancer-induced osteolysis and postmenopausal osteoporosis, are attributed to excessive bone resorption by osteoc......

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