Leptin-depended NLRP3 inflammasome activation in osteoarthritic chondrocytes is mediated by ROS

Mourmoura, E; Papathanasiou, I; Trachana, V; Konteles, V; Tsoumpou, A; Goutas, A; Papageorgiou, AA; Stefanou, N; Tsezou, A

Tsezou, A (通讯作者),Univ Thessaly, Fac Med, Lab Cytogenet & Mol Genet, Biopolis, Larisa 41500, Greece.

MECHANISMS OF AGEING AND DEVELOPMENT, 2022; 208 ():

Abstract

Leptin and ROS are implicated in the regulation of inflammatory pathways including NLRP3-inflammasome. We investigated the functional link between lep......

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