Pharmacokinetics and Tolerability of Zibotentan in Patients with Concurrent Moderate Renal and Moderate Hepatic Impairment

Mercier, AK; Sunnåker, M; Ueckert, S; Pawlik, T; Henricson, E; Molodetskyi, O; Law, GC; Parker, VER; Oscarsson, J

Mercier, AK (通讯作者)，AstraZeneca, R&D, Clin Pharmacol & Quantitat Pharmacol, Clin Pharmacol & Safety Sci, Pepparedsleden 1, S-43183 Gothenburg, Sweden.

CLINICAL PHARMACOKINETICS, 2023; 62 (12): 1713

Abstract

Background and ObjectiveZibotentan, a selective endothelin A receptor antagonist, is in development for chronic liver and kidney disease. The pharmaco......

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