Impact of polymer type, ASD loading and polymer-drug ratio on ASD tablet disintegration and drug release

Zhang, W; Noland, R; Chin, S; Petkovic, M; Zuniga, R; Santarra, B; Conklin, B; Hou, HH; Nagapudi, K; Gruenhagen, JA; Yehl, P; Chen, T

Zhang, W; Chen, T (corresponding author), Genentech Inc, Small Mol Pharmaceut Sci, 1 DNA Way, San Francisco, CA 94080 USA.

INTERNATIONAL JOURNAL OF PHARMACEUTICS, 2021; 592 ():

Abstract

Amorphous solid dispersion (ASD) has become an attractive strategy to enhance solubility and bioavailability of poorly water-soluble drugs. To facilit......

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