CD16+fibroblasts foster a trastuzumab-refractory microenvironment that is reversed by VAV2 inhibition

Liu, XW; Lu, YW; Huang, JY; Xing, Y; Dai, HQ; Zhu, LL; Li, SR; Feng, JW; Zhou, BX; Li, JQ; Xia, QD; Li, J; Huang, M; Gu, YT; Su, SC

Su, SC (通讯作者)，Sun Yat Sen Univ, Sun Yat Sen Mem Hosp, Med Res Ctr, Guangdong Prov Key Lab Malignant Tumor Epigenet &, Guangzhou 510120, Peoples R China.;Su, SC (通讯作者)，Sun Yat Sen Univ, Sun Yat Sen Mem Hosp, Breast Tumor Ctr, Guangzhou 510120, Peoples R China.;Su, SC (通讯作者)，Sun Yat Sen Univ, Affiliated Hosp 3, Dept Infect Dis, Guangzhou 510630, Peoples R China.;Su, SC (通讯作者)，Sun Yat Sen Univ, Zhongshan Sch Med, Dept Immunol & Microbiol, Guangzhou 510080, Peoples R China.;Su, SC (通讯作者)，Sun Yat Sen

CANCER CELL, 2022; 40 (11): 1341

Abstract

The leukocyte Fcy receptor (FcyR)-mediated response is important for the efficacy of therapeutic antibodies; however, little is known about the role o......

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