Kdm2a deficiency in macrophages enhances thermogenesis to protect mice against HFD-induced obesity by enhancing H3K36me2 at the Pparg locus

Chen, LM; Zhang, J; Zou, Y; Wang, FX; Li, JY; Sun, F; Luo, X; Zhang, M; Guo, YC; Yu, QL; Yang, P; Zhou, Q; Chen, ZS; Zhang, HL; Gong, Q; Zhao, JJ; Eizirik, DL; Zhou, ZG; Xiong, F; Zhang, S; Wang, CY

Xiong, F; Zhang, S; Wang, CY (corresponding author), Huazhong Univ Sci & Technol, Ctr Biomed Res, Dept Resp & Crit Care Med, NHC Key Lab Resp Dis,Tongji Hosp,Tongji Med Coll, Wuhan, Peoples R China.

CELL DEATH AND DIFFERENTIATION, ; ():

Abstract

Kdm2a catalyzes H3K36me2 demethylation to play an intriguing epigenetic regulatory role in cell proliferation, differentiation, and apoptosis. Herein ......

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