Synthesis and evaluation of a novel PET ligand, a GSK'963 analog, aiming at autoradiography and imaging of the receptor interacting protein kinase 1 in the brain

Ikenuma, H; Ogata, A; Koyama, H; Ji, B; Ishii, H; Yamada, T; Abe, J; Seki, C; Nagai, Y; Ichise, M; Minamimoto, T; Higuchi, M; Zhang, MR; Kato, T; Ito, K; Suzuki, M; Kimura, Y

Kimura, Y (通讯作者)，Natl Ctr Geriatr & Gerontol NCGG, Ctr Dev Adv Med Dementia, Dept Clin & Expt Neuroimaging, 7-430 Morioka Cho, Aichi 4748511, Japan.;Kimura, Y (通讯作者)，Natl Inst Quantum Sci & Technol QST, Dept Funct Brain Imaging, Chiba, Japan.

EJNMMI RADIOPHARMACY AND CHEMISTRY, 2023; 8 (1):

Abstract

Background: Receptor interacting protein kinase 1 (RIPK1) is a serine/threonine kinase, which regulates programmed cell death and inflammation. Recent......

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