Effects of bis (2-butoxyethyl) phthalate on adrenocortical function in male rats in puberty partially via down-regulating NR5A1/NR4A1/NR4A2 pathways

Liu, MQ; Chen, HQ; Dai, HP; Wang, YY; Li, JJ; Tian, FH; Li, ZR; Ge, RS

Li, ZR (通讯作者),Wenzhou Med Univ, Affiliated Hosp & Yuying Childrens Hosp 2, Dept Pediat Surg, Wenzhou, Zhejiang, Peoples R China.;Li, ZR (通讯作者),Wenzhou Med Univ, Affiliated Hosp & Yuying Childrens Hosp 2, Key Lab Struct Malformat Children Zhejiang Prov, Wenzhou, Zhejiang, Peoples R China.;Ge, RS (通讯作者),Wenzhou Med Univ, Affiliated Hosp & Yuying Childrens Hosp 2, Dept Anesthesiol, Wenzhou, Zhejiang, Peoples R China.

ENVIRONMENTAL TOXICOLOGY, 2022; 37 (10): 2419

Abstract

Phthalates may interfere with the biosynthesis of steroid hormones in the adrenal cortex. Bis (2-butoxyethyl) phthalate (BBOP) is a phthalate containi......

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