A subset of anti-HLA antibodies induces Fc gamma RIIa-dependent platelet activation

Rijkers, M; Saris, A; Heidt, S; Mulder, A; Porcelijn, L; Claas, FHJ; Bierings, R; Leebeek, FWG; Jansen, AJG; Vidarsson, G; Voorberg, J; de Haas, M

Rijkers, M (reprint author), Sanquin AMC Landsteiner Lab, Dept Plasma Prot, Amsterdam, Netherlands.

HAEMATOLOGICA, 2018; 103 (10): 1741

Abstract

HLA antibodies are associated with refractoriness to platelet transfusion, leading to rapid platelet clearance, sometimes coinciding with clinical sid......

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