Densely methylated DNA traps Methyl-CpG-binding domain protein 2 but permits free diffusion by Methyl-CpG-binding domain protein 3

Leighton, GO; Irvin, EM; Kaur, P; Liu, M; You, CJ; Bhattaram, D; Piehler, J; Riehn, R; Wang, H; Pan, H; Jr, DCW

Jr, DCW (通讯作者)，Univ North Carolina Chapel Hill, Sch Med, Dept Pathol, Chapel Hill, NC 27599 USA.;Jr, DCW (通讯作者)，Univ North Carolina Chapel Hill, Sch Med, Lab Med, Chapel Hill, NC 27599 USA.;Pan, H (通讯作者)，North Carolina State Univ, Dept Phys, Raleigh, NC 27695 USA.

JOURNAL OF BIOLOGICAL CHEMISTRY, 2022; 298 (10):

Abstract

The methyl-CpG-binding domain 2 and 3 proteins (MBD2 and MBD3) provide structural and DNA-binding function for the Nucleosome Remodeling and Deacetyla......

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