Extreme longevity variants at the FOXO3 locus may moderate FOXO3 isoform levels

Frankum, R; Jameson, TSO; Knight, BA; Stephens, FB; Wall, BT; Donlon, TA; Torigoe, T; Willcox, BJ; Willcox, DC; Allsopp, RC; Harries, LW

Harries, LW (通讯作者)，Univ Exeter, Med Sch, Inst Biomed & Clin Sci, Barrack Rd, Exeter EX2 5DW, Devon, England.

GEROSCIENCE, 2022; 44 (2): 1129

Abstract

The rs2802292, rs2764264 and rs13217795 variants of FOXO3 have been associated with extreme longevity in multiple human populations, but the mechanism......

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