Definition of Naturally Processed Peptides Reveals Convergent Presentation of Autoantigenic Topoisomerase I Epitopes in Scleroderma

Tiniakou, E; Fava, A; McMahan, ZH; Guhr, T; O'Meally, RN; Shah, AA; Wigley, FM; Cole, RN; Boin, F; Darrah, E

Darrah, E (corresponding author), Johns Hopkins Univ, Div Rheumatol, MFL Ctr Tower Suite 5300,5200 Eastern Ave, Baltimore, MD 21224 USA.; Boin, F (corresponding author), Univ San Francisco, Div Rheumatol, Med Sci Bldg,S-847513 Parnassus Ave, San Francisco, CA 94122 USA.

ARTHRITIS & RHEUMATOLOGY, 2020; 72 (8): 1375

Abstract

Objective Autoimmune responses toDNAtopoisomerase I (topo I) are found in a subset of scleroderma patients who are at high risk for interstitial lung ......

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