Ifenprodil Stereoisomers: Synthesis, Absolute Configuration, and Correlation with Biological Activity

Bechthold, E; Schreiber, JA; Lehmkuhl, K; Frehland, B; Schepmann, D; Bernal, FA; Daniliuc, C; Alvarez, I; Garcia, CV; Schmidt, TJ; Seebohm, G; Wunsch, B

Wunsch, B (corresponding author), Westfalische Wilhelms Univ Munster, Chem Biol Ion Channels Chemb, GRK 2515, D-48149 Munster, Germany.; Wunsch, B (corresponding author), Westfalische Wilhelms Univ Munster, Inst Pharmazeut & Med Chem, D-48149 Munster, Germany.

JOURNAL OF MEDICINAL CHEMISTRY, 2021; 64 (2): 1170

Abstract

Ifenprodil (1) is a potent GluN2B-selective N-methyl-D-aspartate (NMDA) receptor antagonist that is used as a cerebral vasodilator and has been examin......

Full Text Link


Links

期刊讨论 | 中国SCI论文 | 期刊主页 | 投稿经验 | 杂志官网 | 投稿链接 | 作者需知 | PMC链接 | Pubmed全文检索