Two activating mutations of MPL in triple-negative myeloproliferative neoplasms

Xie, J; Chen, XH; Gao, F; Hou, RX; Tian, TT; Zhang, YF; Fan, LF; Hu, JJ; Zhu, GY; Yang, WF; Wang, HW

Wang, HW (reprint author), Shanxi Med Univ, Inst Hematol, Hosp 2, 382 Wuyi Rd, Taiyuan 030001, Shanxi, Peoples R China.

CANCER MEDICINE, 2019; 8 (11): 5254

Abstract

MPLW515K or W515L mutation plays an important role in the pathogenesis of myeloproliferative neoplasms (MPNs) through signaling molecules of the cytok......

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