Tissue Treg Secretomes and Transcription Factors Shared With Stem Cells Contribute to a Treg Niche to Maintain Treg-Ness With 80% Innate Immune Pathways, and Functions of Immunosuppression and Tissue Repair

Zhang, RJ; Xu, KM; Shao, Y; Sun, Y; Saredy, J; Cutler, E; Yao, T; Liu, M; Liu, L; Drummer, C; Lu, YF; Saaoud, F; Ni, D; Wang, JR; Li, YF; Li, RS; Jiang, XH; Wang, H; Yang, XF

Yang, XF (corresponding author), Temple Univ, Lewis Katz Sch Med, Ctr Cardiovasc Res, Philadelphia, PA 19122 USA.; Yang, XF (corresponding author), Temple Univ, Lewis Katz Sch Med, Metab Dis Res & Thrombosis Res, Dept Pharmacol, Philadelphia, PA 19122 USA.; Yang, XF (corresponding author), Temple Univ, Lewis Katz Sch Med, Dept Microbiol, Philadelphia, PA 19122 USA.; Yang, XF (corresponding author), Temple Univ, Lewis Katz Sch Med, Dept Immunol, Philadelphia, PA 19122 USA.; Yang, XF (correspondin

FRONTIERS IN IMMUNOLOGY, 2021; 11 ():

Abstract

We used functional -omics angles and examined transcriptomic heterogeneity in CD4(+)Foxp3(+) regulatory T cells (Treg) from spleen (s-Treg), lymph nod......

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