Computational QSAR model combined molecular descriptors and fingerprints to predict HDAC1 inhibitors

Shi, JS; Zhao, GL; Wei, YB

Wei, YB (reprint author), Fudan Univ, Huashan Hosp, Div Orthopaed Surg, Shanghai, Peoples R China.

M S-MEDECINE SCIENCES, 2018; 34 (): 52

Abstract

The dynamic balance between acetylation and deacetylation of histones plays a crucial role in the epigenetic regulation of gene expression. It is equi......

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