Identification of imidazo[4,5-c]pyridin-2-one derivatives as novel Src family kinase inhibitors against glioblastoma

Zhang, LS; Yang, ZC; Sang, HT; Jiang, Y; Zhou, MF; Huang, CA; Huang, CH; Wu, XY; Zhang, TT; Zhang, XM; Wan, SH; Zhang, JJ

Wan, SH; Zhang, JJ (corresponding author), Southern Med Univ, Sch Pharmaceut Sci, Guangdong Prov Key Lab New Drug Screening, Guangzhou 510515, Peoples R China.

JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, 2021; 36 (1): 1541

Abstract

Glioblastoma multiforme (GBM) is the most common and malignant primary brain tumour in the central nervous system (CNS). As the ideal targets for GBM ......

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