Decrease in an anti-ageing factor, growth differentiation factor 11, in chronic obstructive pulmonary disease

Onodera, K; Sugiura, H; Yamada, M; Koarai, A; Fujino, N; Yanagisawa, S; Tanaka, R; Numakura, T; Togo, S; Sato, K; Kyogoku, Y; Hashimoto, Y; Okazaki, T; Tamada, T; Kobayashi, S; Yanai, M; Miura, M; Hoshikawa, Y; Okada, Y; Suzuki, S; Ichinose, M

Sugiura, H (reprint author), Tohoku Univ, Dept Resp Med, Grad Sch Med, Aoba Ku, 1-1 Seiryo Machi, Sendai, Miyagi 9808574, Japan.

THORAX, 2017; 72 (10): 893

Abstract

Rationale Cellular senescence is observed in the lungs of patients with COPD and may contribute to the disease pathogenesis. Growth differentiation fa......

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