IL-7 and CCL19 expression in CAR-T cells improves immune cell infiltration and CAR-T cell survival in the tumor

Adachi, K; Kano, Y; Nagai, T; Okuyama, N; Sakoda, Y; Tamada, K

Tamada, K (reprint author), Yamaguchi Univ, Grad Sch Med, Dept Immunol, Ube, Yamaguchi, Japan.

NATURE BIOTECHNOLOGY, 2018; 36 (4): 346

Abstract

Infiltration, accumulation, and survival of chimeric antigen receptor T (CAR-T) cells in solid tumors is crucial for tumor clearance. We engineered CA......

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