TAK1ng control: TAK1 restrains NLRP3 activation

Mangan, MS; Latz, E

Latz, E (reprint author), Univ Bonn, Inst Innate Immun, Bonn, Germany.; Latz, E (reprint author), Univ Massachusetts, Sch Med, Dept Infect Dis & Immunol, Worcester, MA 01655 USA.; Latz, E (reprint author), German Ctr Neurodegenerat Dis DZNE, Bonn, Germany

JOURNAL OF EXPERIMENTAL MEDICINE, 2018; 215 (4): 1007

Abstract

In this issue of JEM, Malireddi et al. (https://doi.org/10.1084/jem.20171922) demonstrate that macrophage-specific loss of TAK1 causes spontaneous NLR......

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