An Excitable Ras/PI3K/ERK Signaling Network Controls Migration and Oncogenic Transformation in Epithelial Cells

Zhan, HW; Bhattacharya, S; Cai, HQ; Iglesias, PA; Huang, CH; Devreotes, PN

Devreotes, PN (corresponding author), Johns Hopkins Univ, Sch Med, Dept Biol Chem, Baltimore, MD 21205 USA.; Devreotes, PN (corresponding author), Johns Hopkins Univ, Dept Cell Biol, Sch Med, Baltimore, MD 21205 USA.; Devreotes, PN (corresponding author), Johns Hopkins Univ, Ctr Cell Dynam, Sch Med, Baltimore, MD 21205 USA.; Huang, CH (corresponding author), Johns Hopkins Univ, Sch Med, Dept Pathol, Baltimore, MD 21205 USA.

DEVELOPMENTAL CELL, 2020; 54 (5): 608

Abstract

The Ras/PI3K/extracellular signal-regulated kinases (ERK) signaling network plays fundamental roles in cell growth, survival, and migration and is fre......

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