The Endothelin-A Receptor Antagonist Zibotentan Induces Damage to the Nasal Olfactory Epithelium Possibly Mediated in Part through Type 2 Innate Lymphoid Cells

Esvelt, MA; Freeman, ZT; Pearson, AT; Harkema, JR; Clines, GT; Clines, KL; Dyson, MC; Hoenerhoff, MJ

Esvelt, MA (reprint author), Univ Texas Southwestern Med Ctr Dallas, 5323 Harry Hines Blvd,LRSB JA Bldg 4th Floor, Dallas, TX 75390 USA.

TOXICOLOGIC PATHOLOGY, 2019; 47 (2): 150

Abstract

Zibotentan, an endothelin-A receptor antagonist, has been used in the treatment of various cardiovascular disorders and neoplasia. Castrated athymic n......

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