4-octyl Itaconate inhibits lipopolysaccharide (LPS)-induced osteoarthritis via activating Nrf2 signalling pathway

Zhang, QC; Bai, XH; Wang, RR; Zhao, H; Wang, LL; Liu, JW; Li, M; Chen, Z; Wang, ZJ; Li, LX; Wang, DW

Wang, DW (通讯作者)，Shandong Univ, Shandong Prov Hosp, Cheeloo Coll Med, Dept Orthopaed, 324 Rd Jing Wu Wei Qi, Jinan 250021, Shandong, Peoples R China.

JOURNAL OF CELLULAR AND MOLECULAR MEDICINE, 2022; 26 (5): 1515

Abstract

Small molecule drug intervention for chondrocytes is a valuable method for the treatment of osteoarthritis (OA). The 4-octyl itaconate (OI) is a cellu......

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