RNA targeting with CRISPR-Cas13

Abudayyeh, OO; Gootenberg, JS; Essletzbichler, P; Han, S; Joung, J; Belanto, JJ; Verdine, V; Cox, DBT; Kellner, MJ; Regev, A; Lander, ES; Voytas, DF; Ting, AY; Zhang, F

Zhang, F (reprint author), Broad Inst MIT & Harvard, Cambridge, MA 02142 USA.; Zhang, F (reprint author), MIT, McGovern Inst Brain Res, 77 Massachusetts Ave, Cambridge, MA 02139 USA.; Zhang, F (reprint author), MIT, Dept Brain & Cognit Sci, E25-618, Cambr

NATURE, 2017; 550 (7675): 280

Abstract

RNA has important and diverse roles in biology, but molecular tools to manipulate and measure it are limited. For example, RNA interference(1-3) can e......

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