Design, synthesis, and biological evaluation of arylmethylpiperidines as Kv1.5 potassium channel inhibitors

Zhao, LY; Yang, Q; Tang, YQ; You, QD; Guo, XK

You, QD; Guo, XK (通讯作者)，China Pharmaceut Univ, Sch Pharm, Dept Med Chem, Nanjing 210009, Peoples R China.

JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, 2022; 37 (1): 462

Abstract

Kv1.5 potassium channel, encoded by KCNA5, is a promising target for the treatment of atrial fibrillation, one of the common arrhythmia. A new series ......

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