PrP Knockout Cells Expressing Transmembrane PrP Resist Prion Infection

Marshall, KE; Hughson, A; Vascellari, S; Priola, SA; Sakudo, A; Onodera, T; Baron, GS

Baron, GS (reprint author), NIAID, Rocky Mt Labs, Persistent Viral Dis Lab, NIH, Hamilton, MT 59840 USA.

JOURNAL OF VIROLOGY, 2017; 91 (2):

Abstract

Glycosylphosphatidylinositol (GPI) anchoring of the prion protein (PrPC) influences PrPC misfolding into the disease-associated isoform, PrPres, as we......

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