The underlying mechanisms of lorlatinib penetration across the blood-brain barrier and the distribution characteristics of lorlatinib in the brain

Chen, W; Jin, DJ; Shi, YF; Zhang, YJ; Zhou, HY; Li, GH

Li, GH (corresponding author), Chinese Acad Med Sci & Peking Union Med Coll, Natl Canc Ctr, Dept Pharm, Canc Hosp,Natl Clin Res Ctr Canc, Beijing 100021, Peoples R China.

CANCER MEDICINE, 2020; 9 (12): 4350

Abstract

Objective To clarify the distribution of lorlatinib in the brain and elucidate the molecular mechanisms of lorlatinib penetration across the blood-bra......

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