Absence of miR-146a in Podocytes Increases Risk of Diabetic Glomerulopathy via Up-regulation of ErbB4 and Notch-1

Lee, HW; Khan, SQ; Khaliqdina, S; Altintas, MM; Grahammer, F; Zhao, JL; Koh, KH; Tardi, NJ; Faridi, MH; Geraghty, T; Cimbaluk, DJ; Susztak, K; Moita, LF; Baltimore, D; Tharaux, PL; Huber, TB; Kretzler, M; Bitzer, M; Reiser, J; Gupta, V

Gupta, V (reprint author), Rush Univ, Med Ctr, Dept Internal Med, Cohn 222, Chicago, IL 60026 USA.

JOURNAL OF BIOLOGICAL CHEMISTRY, 2017; 292 (2): 732

Abstract

Podocyte injury is an early event in diabetic kidney disease and is a hallmark of glomerulopathy. MicroRNA-146a (miR-146a) is highly expressed in many......

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