alpha-Synuclein-induced Kv4 channelopathy in mouse vagal motoneurons drives nonmotor parkinsonian symptoms

Chiu, WH; Kovacheva, L; Musgrove, RE; Arien-Zakay, H; Koprich, JB; Brotchie, JM; Yaka, R; Ben-Zvi, D; Hanani, M; Roeper, J; Goldberg, JA

Goldberg, JA (corresponding author), Hebrew Univ Jerusalem, Fac Med, Inst Med Res Israel Canada, Dept Med Neurobiol, IL-9112102 Jerusalem, Israel.

SCIENCE ADVANCES, 2021; 7 (11):

Abstract

No disease-modifying therapy is currently available for Parkinson's disease (PD), the second most common neurodegenerative disease. The long nonmotor ......

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