Design and Fabrication of the Vertical-Flow Bioreactor for Compaction Hepatocyte Culture in Drug Testing Application

Zhu, L; Wang, ZF; Xia, HM; Yu, H

Yu, H (corresponding author), Natl Univ Singapore, Mechanobiol Inst, T Lab, 05-01,5A Engn Dr 1, Singapore 117411, Singapore.; Yu, H (corresponding author), ASTAR, Inst Biotechnol & Nanotechnol, 04-01,31 Biopolis Way, Singapore 138669, Singapore.; Yu, H (corresponding author), Yong Loo Lin Sch Med, Dept Physiol, MD9-04-11,2 Med Dr, Singapore 117597, Singapore.; Yu, H (corresponding author), Singapore MIT Alliance Res & Technol, 1 CREATE Way,10-01 CREATE Tower, Singapore 138602, Singapore.

BIOSENSORS-BASEL, 2021; 11 (5):

Abstract

The perfusion culture of primary hepatocytes has been widely adopted to build bioreactors for various applications. As a drug testing platform, a uniq......

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