Integrative computational approach identifies drug targets in CD4(+) T-cell-mediated immune disorders

Puniya, BL; Amin, R; Lichter, B; Moore, R; Ciurej, A; Bennett, SJ; Shah, A; Barberis, M; Helikar, T

Helikar, T (corresponding author), Univ Nebraska Lincoln, Dept Biochem, Lincoln, NE 68588 USA.; Barberis, M (corresponding author), Univ Surrey, Sch Biosci & Med, Fac Hlth & Med Sci, Syst Biol, Guildford, Surrey, England.; Barberis, M (corresponding author), Univ Surrey, Ctr Math & Computat Biol, Guildford, Surrey, England.; Barberis, M (corresponding author), Univ Amsterdam, Swammerdam Inst Life Sci, Synthet Syst Biol & Nucl Org, Amsterdam, Netherlands.

NPJ SYSTEMS BIOLOGY AND APPLICATIONS, 2021; 7 (1):

Abstract

CD4(+) T cells provide adaptive immunity against pathogens and abnormal cells, and they are also associated with various immune-related diseases. CD4(......

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