ATG5 Mediates a Positive Feedback Loop between Wnt Signaling and Autophagy in Melanoma

Ndoye, A; Budina-Kolomets, A; Kugel, CH; Webster, MR; Kaur, A; Behera, R; Rebecca, VW; Li, L; Brafford, PA; Liu, Q; Gopal, YNV; Davies, MA; Mills, GB; Xu, XW; Wu, H; Herlyn, M; Nicastri, MC; Winkler, JD; Soengas, MS; Amaravadi, RK; Murphy, ME; Weerar

Weeraratna, AT (reprint author), Wistar Inst Anat & Biol, 3601 Spruce St, Philadelphia, PA 19104 USA.

CANCER RESEARCH, 2017; 77 (21): 5873

Abstract

Autophagy mediates resistance to various anticancer agents. In melanoma, resistance to targeted therapy has been linked to expression of Wnt5A, an int......

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