ERCC6L2 promotes DNA orientation-specific recombination in mammalian cells

Liu, XJ; Liu, TT; Shang, YF; Dai, PF; Zhang, WB; Lee, BJ; Huang, M; Yang, DP; Wu, Q; Liu, LD; Zheng, XQ; Zhou, BO; Dong, JC; Yeap, LS; Hu, JZ; Xiao, TF; Zha, S; Casellas, R; Liu, XS; Meng, FL

Meng, FL (corresponding author), Chinese Acad Sci, Ctr Excellence Mol Cell Sci, Shanghai Inst Biochem & Cell Biol, State Key Lab Mol Biol, Shanghai 200031, Peoples R China.; Meng, FL (corresponding author), Univ Chinese Acad Sci, Beijing 100049, Peoples R China.

CELL RESEARCH, 2020; 30 (9): 732

Abstract

Programmed DNA recombination in mammalian cells occurs predominantly in a directional manner. While random DNA breaks are typically repaired both by d......

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