Disease-modifying effects of edasalonexent, an NF-KB inhibitor, in young boys with Duchenne muscular dystrophy: Results of the MoveDMD phase 2 and open label extension trial

Finkel, RS; Finanger, E; Vandenborne, K; Sweeney, HL; Tennekoon, G; Shieh, PB; Willcocks, R; Walter, G; Rooney, WD; Forbes, SC; Triplett, WT; Yum, SW; Mancini, M; MacDougall, J; Fretzen, A; Bista, P; Nichols, A; Donovan, JM

Finkel, RS (corresponding author), St Jude Childrens Res Hosp, 332 N Lauderdale St, Memphis, TN 38105 USA.; Finkel, RS (corresponding author), Nemours Childrens Hosp, Orlando, FL 32827 USA.

NEUROMUSCULAR DISORDERS, 2021; 31 (5): 385

Abstract

Chronic activation of NF- kappa B is a key driver of muscle degeneration and suppression of muscle regeneration in Duchenne muscular dystrophy. Edasal......

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