Influence of the C-5 substitution in polysubstituted pyrimidines on inhibition of prostaglandin E-2 production

Kolman, V; Kalcic, F; Jansa, P; Zidek, Z; Janeba, Z

Janeba, Z (reprint author), Czech Acad Sci, Inst Organ Chem & Biochem, Flemingovo Nam 2, Prague 16610 6, Czech Republic.; Zidek, Z (reprint author), Czech Acad Sci, Inst Expt Med, Videnska 1083, Prague 14220 4, Czech Republic.

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018; 156 (): 295

Abstract

As a part of a broader structure-activity relationship study of substituted 2-aminopyrimidines, the influence of the C-5 substitution on inhibition of......

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