Clinically relevant GSK-3 beta inhibitor 9-ING-41 is active as a single agent and in combination with other antitumor therapies in human renal cancer

Anraku, T; Kuroki, H; Kazama, A; Bilim, V; Tasaki, M; Schmitt, D; Mazar, A; Giles, FJ; Ugolkov, A; Tomita, Y

Tomita, Y (corresponding author), Niigata Univ, Grad Sch Med & Dent Sci, Div Mol Oncol, Dept Urol,Chuo Ward, 1-757 Asahimachi Dori, Niigata, Niigata 9518510, Japan.

INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE, 2020; 45 (2): 315

Abstract

Glycogen synthase kinase-3 (GSK-3), a serine/threonine kinase, is involved in a broad range of pathological processes including cancer. GSK-3 has two ......

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