Downregulation of miR-214-3p attenuates mesangial hypercellularity by targeting PTEN-mediated JNK/c-Jun signaling in IgA nephropathy

Li, Y; Xia, M; Peng, L; Liu, HY; Chen, GC; Wang, C; Yuan, D; Liu, Y; Liu, H

Liu, H (corresponding author), Cent South Univ, Xiangya Hosp 2, Dept Nephrol, Hunan Key Lab Kidney Dis & Blood Purificat, 139 Renmin Middle Rd, Changsha 410011, Hunan, Peoples R China.

INTERNATIONAL JOURNAL OF BIOLOGICAL SCIENCES, 2021; 17 (13): 3343

Abstract

Mesangial cell (MC) proliferation and matrix expansion are basic pathological characteristics of IgA nephropathy (IgAN). However, the stepwise mechani......

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