Heparanase overexpression impedes perivascular clearance of amyloid-beta from murine brain: relevance to Alzheimer's disease

Zhang, X; O'Callaghan, P; Li, HL; Tan, YX; Zhang, GL; Barash, U; Wang, XM; Lannfelt, L; Vlodavsky, I; Lindahl, U; Li, JP

Li, JP (corresponding author), Uppsala Univ, Dept Med Biochem & Microbiol, SciLifeLab Uppsala, Biomed Ctr, Husargatan 3,Box 582, S-75123 Uppsala, Sweden.

ACTA NEUROPATHOLOGICA COMMUNICATIONS, 2021; 9 (1):

Abstract

Defective amyloid-beta (A beta) clearance from the brain is a major contributing factor to the pathophysiology of Alzheimer's disease (AD). A beta cle......

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