A cFLIP-flop switch for senolysis

Fan, DNY; Schmitt, CA

Schmitt, CA (通讯作者),Charite, Med Dept Hematol Oncol & Tumor Immunol, Mol Krebsforschungszentrum, Berlin, Germany.;Schmitt, CA (通讯作者),Max Delbruck Ctr Mol Med, Helmholtz Assoc, Berlin, Germany.;Schmitt, CA (通讯作者),Johannes Kepler Univ Linz, Linz, Austria.;Schmitt, CA (通讯作者),Kepler Univ Hosp, Dept Hematol & Oncol, Linz, Austria.;Schmitt, CA (通讯作者),Deutsch Konsortium Translat Krebsforsch, Berlin, Germany.

NATURE CANCER, 2022; 3 (11): 1279

Abstract

Persistent senescent cancer cells have tumor-promoting potential, making their selective elimination a prime therapeutic objective. The death receptor......

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