Fargesin ameliorates osteoarthritis via macrophage reprogramming by downregulating MAPK and NF-kappa B pathways

Lu, JS; Zhang, HB; Pan, JY; Hu, ZQ; Liu, LL; Liu, YL; Yu, X; Bai, XC; Cai, DZ; Zhang, HY

Zhang, HY (corresponding author), Southern Med Univ, Ctr Orthopaed Surg, Dept Joint Surg, Affiliated Hosp 3, Guangzhou, Peoples R China.; Zhang, HY (corresponding author), Southern Med Univ, Orthoped Hosp Guangdong Prov, Acad Orthoped Guangdong Prov, Dept Orthoped,Affiliated Hosp 3, Guangzhou, Peoples R China.; Zhang, HY (corresponding author), Southern Med Univ, Sch Clin Med 3, Guangzhou, Peoples R China.; Zhang, HY (corresponding author), Guangdong Prov Key Lab Bone & Joint Degenerat Dis, Guan

ARTHRITIS RESEARCH & THERAPY, 2021; 23 (1):

Abstract

Background To investigate the role and regulatory mechanisms of fargesin, one of the main components of Magnolia fargesii, in macrophage reprogramming......

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