Syntheses and Antiproliferative Evaluation of 6-Thienyl, 6-Polyphenyl Aryl and 6-Naphthyl Derivatives of 2,4-Diaminopyrido [3,2-d]pyramidine as Non-classical Antifolate Targeting DHFR

Yang, JJ; Wang, M; Li, X; Fan, NN; Xue, LM; Li, H; Tian, C; Wang, XW; Liu, JY; Zhang, ZL

Zhang, ZL (reprint author), Peking Univ, Sch Pharmaceut Sci, Dept Chem Biol, Beijing 100191, Peoples R China.

CHEMICAL RESEARCH IN CHINESE UNIVERSITIES, 2017; 33 (4): 559

Abstract

A series of 6-thienylethenyl, 6-polyphenyl arylethenyl, 6-thienylethyl and 6-polyphenyl arylethyl derivatives of 2,4-cliaminopyrido[3,24pyrimidine for......

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