Role of membrane structure on the filtrate flux during monoclonal antibody filtration through virus retentive membranes

Billups, M; Minervini, M; Holstein, M; Feroz, H; Ranjan, S; Hung, J; Bao, HY; Li, ZJ; Ghose, S; Zydney, AL

Zydney, AL (通讯作者),Penn State Univ, Dept Chem Engn, 404 Chem & Biomed Engn Bldg, University Pk, PA 16802 USA.

BIOTECHNOLOGY PROGRESS, 2022; 38 (2):

Abstract

Virus removal filtration is a critical step in the manufacture of monoclonal antibody products, providing a robust size-based removal of both envelope......

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