Structural basis of von Willebrand factor multimerization and tubular storage

Zeng, JW; Shu, ZM; Liang, Q; Zhang, J; Wu, WM; Wang, XF; Zhou, AW

Zhou, AW (通讯作者)，Shanghai Jiao Tong Univ, Sch Med, Dept Pathophysiol, Key Lab Cell Differentiat & Apoptosis,Chinese Min, Shanghai 200025, Peoples R China.;Zeng, JW (通讯作者)，Tsinghua Univ, State Key Lab Membrane Biol, Beijing Adv Innovat Ctr Struct Biol, Sch Life Sci, Beijing 100084, Peoples R China.;Wang, XF (通讯作者)，Shanghai Jiao Tong Univ, Sch Med, Ruijin Hosp, Dept Lab Med, Shanghai 200025, Peoples R China.

BLOOD, 2022; 139 (22): 3314

Abstract

The von Willebrand factor (VWF) propeptide (domains D1D2) is essential for the assembly of VWF multimers and its tubular storage in Weibel-Palade bodi......

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