Spectrum of activity of dasatinib against mutant KIT kinases associated with drug-sensitive and drug-resistant gastrointestinal stromal tumors

Zeng, CL; Zhu, L; Jia, XN; Pang, YZ; Li, Z; Lu, XJ; Xie, FF; Duan, LL; Wang, YX

Wang, YX (corresponding author), Chinese Acad Sci, Univ Chinese Acad Sci, Changzheng Hosp,Inst Translat Med CAS SMMU,CAS Ke, SINH Changzheng Hosp Joint Ctr Translat Med,Shang, 320 Yue Yang Rd, Shanghai 200031, Peoples R China.

GASTRIC CANCER, 2020; 23 (5): 837

Abstract

Background The majority of GISTs express mutationally activated KIT. Imatinib and sunitinib are approved KIT-inhibiting therapies. Their efficacy is u......

Full Text Link