Autonomous sensing of the insulin peptide by an olfactory G protein-coupled receptor modulates glucose metabolism

Cheng, J; Yang, Z; Ge, XY; Gao, MX; Meng, R; Xu, X; Zhang, YQ; Li, RZ; Lin, JY; Tian, ZM; Wang, J; Ning, SL; Xu, YF; Yang, F; Gu, JK; Sun, JP; Yu, X

Yu, X (通讯作者)，Shandong Univ, Sch Basic Med Sci, Key Lab Expt Teratol, Minist Educ, Jinan 250012, Shandong, Peoples R China.;Yu, X (通讯作者)，Shandong Univ, Sch Basic Med Sci, Dept Physiol & Pathophysiol, Jinan 250012, Shandong, Peoples R China.;Sun, JP (通讯作者)，Shandong Univ, Adv Med Res Inst, Jinan 250012, Shandong, Peoples R China.;Sun, JP (通讯作者)，Peking Univ, Key Lab Mol Cardiovasc Sci, Minist Educ, Dept Physiol & Pathophysiol,Sch Basic Med Sci, Beijing 100191, Peoples R China.

CELL METABOLISM, 2022; 34 (2): 240

Abstract

Along with functionally intact insulin, diabetes-associated insulin peptides are secreted by beta cells. By screening the expression and functional ch......

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