HBV X protein-based therapeutic vaccine accelerates viral antigen clearance by mobilizing monocyte infiltration into the liver in HBV carrier mice

Horng, JH; Lin, WH; Wu, CR; Lin, YY; Wu, LL; Chen, DS; Chen, PJ

Chen, PJ (corresponding author), Natl Taiwan Univ, Grad Inst Microbiol, Coll Med, 1 Jen Ai Rd Sect 1, Taipei, Taiwan.; Chen, PJ (corresponding author), Natl Taiwan Univ, Grad Inst Clin Med, Coll Med, 1,Jen Ai Rd Sect 1, Taipei, Taiwan.; Chen, PJ (corresponding author), Natl Taiwan Univ Hosp, Dept Internal Med, Div Gastroenterol, 1 Changde St, Taipei, Taiwan.; Chen, PJ (corresponding author), Natl Taiwan Univ Hosp, Hepatitis Res Ctr, 1 Changde St, Taipei, Taiwan.

JOURNAL OF BIOMEDICAL SCIENCE, 2020; 27 (1):

Abstract

Background Hepatitis B virus (HBV) persistently infected about 250 million people worldwide, and a curative treatment remains an unmet medical need. A......

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